理学部化学科

メニュー

桑原俊介／教授

氏名

桑原俊介（Shunsuke Kuwahara）

経歴

青山学院大学理工学部化学科卒業
東北大学大学院理学研究科化学専攻博士前期課程修了
日本学術振興会特別研究員（DC2）
東北大学大学院理学研究科化学専攻博士後期課程中退
東北大学多元物質科学研究所助手
博士（理学）取得（東北大学）
東北大学多元物質科学研究所助教
東邦大学理学部化学科講師, 准教授を経て, 同教授
米国ライス大学客員研究員（2014.9-2016.3）

専門分野

構造有機化学
超分子化学

主な研究課題

新規分子マシンの合成と機能評価
キラル化合物の合成、分子認識、絶対配置決定法の開発

主な研究業績

＜論文＞

S. Kuwahara, Y. Suzuki, N. Sugita, M. Ikeda, F. Nagatsugi, N. Harada, Y. Habata (2018):
Thermal E/Z Isomerization in First Generation Molecular Motors, J. Org. Chem., 2018, 83, 4800-4804.
S. Kuwahara, N. Tasaki, Y. Suzuki, M. Nakagawa, M. Ikeda, Y. Habata (2017):
3-Menthoxybiphenyl-4-carboxylic Acid: A Versatile Reagent for Chiral Resolution and Determination of the Absolute Stereochemistry of Aromatic Alcohols,Tetrahedron: Asymmetry., 2017, 28, 945-953.
V. García-López, J. Jeffet, S. Kuwahara, A. A. Martí, Y. Ebenstein, J. M. Tour (2016):
Synthesis and Photostability of Unimolecular Submersible Nanomachines: Toward Single-Molecule Tracking in Solution, Org. Lett., 2016, 18, 2343-2346.
S. Kuwahara, M. Nakamura, A. Yamaguchi, M. Ikeda, Y. Habata (2013):
Combination of a New Chiroptical Probe and Theoretical Calculations for Chirality Detection of Primary Amines, Org. Lett., 2013, 14, 5738-5741.
S. Kuwahara, R. Chamura, S. Tsuchiya, M. Ikeda, Y. Habata (2013):
Chirality Transcription and Amplification by [2]Pseudorotaxanes, Chem. Commun., 2013, 49, 2186-2188.
F. Nagatsugi, Y. Takahashi, M. Kobayashi, S. Kuwahara, S. Kusano, T. Chikuni, S. Hagihara, N. Harada (2013):
Synthesis of Peptide-conjugated Light-driven Molecular Motors and Evaluation of Their DNA-binding Properties, Mol. BioSyst., 2013, 9, 969-973.
S. Kuwahara, K. Obata, T. Fujita, N. Miura, A. Nakahashi, K. Monde, N. Harada (2010):
(R)-(+)-[VCD(–)984]-4-Ethyl-4-methyloctane, a Cryptochiral Hydrocarbon with a Quaternary Chirality Center. (2) Vibrational CD Spectra of Both Enantiomers and Absolute Configurational Assignment, Eur. J. Org. Chem., 2010, 6385-6392.
S. Kuwahara, J. Naito, Y. Yamamoto, Y. Kasai, T. Fujita, K. Noro, K. Shimanuki, M. Akagi, M., Watanabe, T. Matsumoto, M. Watanabe, A. Ichikawa, N. Harada (2007):
Crystalline State Conformational Analysis of MαNP Esters, Powerful Resolution and Chiral ¹H NMR Anisotropy Tools, Eur. J. Org. Chem., 2007, 1827-1840.
S. Kuwahara, K. Obata, K. Yoshida, T. Matsumoto, N. Harada, N. Yasuda, Y. Ozawa, K. Toriumi (2005):
Conclusive Determination of the Absolute Stereochemistry of Chiral C₆₀ Fullerene Bis-Adducts of Cis-3 Type by X-ray Crystallography and CD Spectra, Angew. Chem. Int. Ed., 2005, 44, 2262-2265.
T. Fujita, S. Kuwahara, N. Harada (2005):
A New Model of Light Powered Chiral Molecular Motor with Higher Speed of Rotation, Part 1 -Synthesis and Absolute Stereostructure, Eur. J. Org. Chem., 2005, 4533-4543.
S. Kuwahara, T. Fujita, N. Harada (2005):
A New Model of Light Powered Chiral Molecular Motor with Higher Speed of Rotation, Part 2 -Dynamics of Motor Rotation, Eur. J. Org. Chem., 2005, 4544-4556.

＜総説・著書＞

S. Kuwahara, M. Ikeda, Y. Habata (2018):
Chiroptical Probes for Determination of Absolute Stereochemistry by CD Exciton Chirality Method. In Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, 2nd Edition, P. L. Polavarapu, Ed., Chapter 8, Elsevier, 2018, 345-366.
N. Harada,S. Kuwahara (2012):
CD Spectra of Chiral Extended π-Electron Compounds: Theoretical Determination of the Absolute Stereochemistry and Experimental Verification. In Comprehensive Chiroptical Spectroscopy , N. Berova, P. Polavarapu, K. Nakanishi, R. Woody, Ed., Volume 2, Chapter 5, John Wiley & Sons, 2012, 167-215.